The TRial Of Preventing HYpertension (TROPHY)

The TRial Of Preventing HYpertension (TROPHY)

TROPHY – hypothesis

The TRial Of Preventing HYpertension (TROPHY) is an investigator-initiated trial to examine whether early treatment of high-normal blood pressure values (according to JNC VI) with candesartan would prevent or postpone the development of stage 1 hypertension.

TROPHY – objectives

Primary:

  • to determine whether treatment with candesartan 16 mg compared with placebo reduces the incidence of hypertension in subjects with high-normal BP

Secondary:

  • evaluate reduction of BP after 2 years of treatment with candesartan 16 mg versus placebo
  • evaluate incidence of hypertension after 2 years of treatment with candesartan 16 mg versus placebo
  • evaluate quality of life during 2 years of treatment with candesartan 16 mg versus placebo

 

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