20 Aug The TRial Of Preventing HYpertension (TROPHY)
Posted at 10:26h
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TROPHY – hypothesis
The TRial Of Preventing HYpertension (TROPHY) is an investigator-initiated trial to examine whether early treatment of high-normal blood pressure values (according to JNC VI) with candesartan would prevent or postpone the development of stage 1 hypertension.
TROPHY – objectives
Primary:
- to determine whether treatment with candesartan 16 mg compared with placebo reduces the incidence of hypertension in subjects with high-normal BP
Secondary:
- evaluate reduction of BP after 2 years of treatment with candesartan 16 mg versus placebo
- evaluate incidence of hypertension after 2 years of treatment with candesartan 16 mg versus placebo
- evaluate quality of life during 2 years of treatment with candesartan 16 mg versus placebo
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